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KMID : 1059520100540010059
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Journal of the Korean Chemical Society
2010 Volume.54 No. 1 p.59 ~ p.64
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Synthesis and Antimicrobial Screening of Some Fluorinated Azoles Containing (2-(6-Methyl-2-P-tolyl-lH-imidazo[1,2-a]pyridin-3-yl) Nucleus
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Sharad Shelke
Nilesh Salunkhe
Sandeep Sangale
Swapnil Bhalerao
Ganesh Mhaske
Ranjana Jadhav
Bhausaheb Karale
Nilesh Naik
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Abstract
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The synthesis of a series of fluorinated thiadiazoles 3, triazoles 4 and oxadiazoles 5 are synthesized from thiosemicarbazides 2 containing (2-(6-methyl-2-p-tolyl-lH-imidazo[1,2-a]pyridin-3-yl nucleus. These reactions were carried out by conventional method as well as ultra sound irradiation method. All products have been characterized by IR, 1H NMR, MS study and screened for their antimicrobial activity.
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KEYWORD
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Fluorinated azoles, Triazoles, Thiadiazoles, Oxadiazoles, Ultrasound, Antibacterial activity
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